qFlamma® Black01 Biotin is an Avidin and Streptavidin reactive form of universal dark quencher that the range of absorption covers from 400 to 800 nm with no native fluorescence. Black01 quencher displays high absorption coefficient, superb stability and aqueous solubility. Biotin-Avidin/Streptavidin binding has high affinity and specificity, which has been exploited for diverse applications in biochemical and biological research fields. We offer qFlamma® Black01 Biotin as suitable dark quencher for designing a variety of activatable probes for affinity chromatography, PCR, in situ nucleic acid hybridization, multiplexed bio-analysis, etc.