Fluorescent Polystyrene Beads

Flamma^® PS bead series are fluorescent spherical particles in the colloidal size made up of high-grade polystyrene (PS) doped with our proprietary dyes. Polystyrene beads are not cytotoxic, and they diffuse minimally from the injection site and persist for long periods in nerve cells. Our fluorescent beads display excellent optical properties yet negligible photobleaching under the intense excitation for fluorescence microscopy. The intense fluorescence and spherical shape of Flamma^® PS bead series enable to generate stronger signals with small amount of probes in many tracing experiments. To decrease nonspecific binding and provide additional functional groups for conjugation, exteriors of PS bead are equipped with carboxylic acids. These pendent carboxylic acids allow them suitable for covalent coupling of proteins and other amine-containing biomolecules by using water-soluble coupling reagents.

BioActs provides various sizes of Flamma^® PS bead series (0.1 – 0.5 μm) in order to meet the diverse needs of our customer, and sizes specified in the product names are nominal bead diameters. These effective fluorescent PS beads can be utilized in a variety of applications such as neuronal tracers, cellular antigen markers, cell tracers, and the standardization reagents for flow cytometry. Due to their high fluorescence intensity, Flamma^® PS bead series are suitable for the many nanoparticle based diagnostic tests, including tracking particles and cells, tracing fluid dynamics, discriminating the size dependence of uptake or transport in vivo. Although limited sizes of our fluorescent beads are available, we can prepare custom-sized particles, custom-dyed or custom-surface modifications orders upon request. Please contact our custom service for further information.

 Figure 1. TEM(Transmission Electron Microscope) image and fluorescence spectra of FlammaBead® Europium