qFlamma® Black01 Thiol

Catalog No. QWT1001
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1 mg $231.00
5 mg $830.00
25 mg $3,087.00
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Description

qFlamma® Black01 Thiol is an inactive form of universal dark quencher that the range of absorption covers from 400 to 800 nm with no native fluorescence. Black01 quencher displays high absorption coefficient, superb stability and aqueous solubility. The thiol is attached to Black01 quencher through a spacer. qFlamma® Black01 thiol can be labeled to thiol of probes or biomolecules through a disulfide bond formation or can be utilized as a reference standard for fluorophore-quencher pair probes. 

Specifications


Functionality: Dark quencher

Functional group: Thiol

Absorption max. (nm): 484

Absorption range (nm): 400 ~ 800

Appearance: Green Solid

Molecular Weight: 780.89 g/mol

Solubility: Water, DMF, DMSO

Storage conditions: -20 ℃, protect from light




Citation & Reference

1. Arnaud Chevalier. Bioconjugatable Azo-Based Dark-Quencher Dyes: Synthesis and Application to Protease-Activatable Far-Red Fluorescent Probes. Chemistry 19.5 (2013): 1686-99.

 

2. Arnaud Chevalier. Universal Dark Quencher Based on “Clicked” Spectrally Distinct Azo Dyes. Org. Lett 2013 15.23 (2013): 6082–6085.


3. Arnaud Chevalier. Straightforward synthesis of bioconjugatable azo dyes. Part 1: Black Hole Quencher-1 (BHQ-1) scaffold. Tetrahedron Letters 55.50 (2014): 6759-6763.

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