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FAM ADIBO
Catalog No. DWF1001
| PACKING UNIT | price |
Lead time |
|---|---|---|
| 1 mg | $121.00 | |
| 5 mg | $279.00 | |
| 25 mg | $552.00 |
Description
FAM ADIBO is a strain-promoted azide-alkyne cycloaddition (SPAAC) reagent of bright green dye used to generate a stable fluorescence signal in bioimaging. The maxima of Ex/Em values are at 494/522 nm, similar to that of Alexa 488 and Cy2. FAM might be excited using 488 nm laser line and displays good optical property. FAM ADIBO couples with an azide to form 1,4-disubstituted 1,2,3-triazole inside of living systems without using any coupling reagents or catalyst nor interfering native biochemical processes. Prior to perform SPAAC, the azide functionality should be introduced onto counterpart biomolecule by means of chemical or genetic modification. We offer FAM ADIBO as a SPAAC reagent dye for cellular imaging and nucleotide functionalization.
Citation & Reference
1. PYARE L. KHANNAA. 4',5'-Dimethoxy-6-carboxyfluorescein: a novel dipole-dipole coupled fluorescence energy transfer acceptor useful for fluorescence immunoassays. Anal Biochem 108.1 (1980): 156-61.
2. Torimura M. Fluorescence-quenching phenomenon by photoinduced electron transfer between a fluorescent dye and a nucleotide base. Anal Sci 17.1 (2001): 155-60.
3. Sylvie Soulie-Begu. In-vivo pharmacokinetic study of two fluorescein derivatives by fluorescence spectroscopy. Optical Biopsies 2627 (1995).
4. Danny van Lierop. Positively charged silver nanoparticles and their effect on Surfaceenhanced Raman scattering of dye-labelled oligonucleotides. Chem. Commun 48 (2012): 8192-8194.
5. Pete Theisen. Fluorescent Dye Phosphoramidite Labelling of Oligonucleotides. Tetrahedron Letters 33.35 (1992): 5033-5036.
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