log
My
Contact
>
Products
>
>
>
Flamma® Fluors Maleimide
>
Flamma® 552 Maleimide
- Flamma® Fluors NHS ester
- Flamma® Fluors Sulfo-NHS ester
- Flamma® Fluors Vinylsulfone
- Flamma® Fluors Isothiocyanate
- Flamma® Fluors Maleimide
- Flamma® Fluors Hydrazide
- Flamma® Fluors Dichlorotriazine
- Flamma® Fluors Carboxylic acid
- Flamma® Fluors Amine
- Flamma® Fluors Thiol
- Flamma® Fluors Alkyne
- Flamma® Fluors PEG4-Alkyne
- Flamma® Fluors ADIBO
- Flamma® Fluors Azide
Flamma® 552 Maleimide
Catalog No. CWM1058
| PACKING UNIT | price |
Lead time |
|---|---|---|
| 1 mg | $121.00 | |
| 5 mg | $420.00 | |
| 25 mg | $840.00 |
Description
Flamma® Fluors 552 Maleimide is a thiol reactive bright yellow dye that used to generate a stable fluorescence signal in bioimaging. The maxima of Ex/Em values are at 550/564 nm, similar to that of Alexa 555, DyLight 549 ATTO 550 and Cy 3. Flamma 552 might be excited using 543, 546 or 555 nm laser line and displays excellent optical property. Flamma 552 maleimide can be conjugated to low-abundance of biomolecules with great sensitivity allowing sensitive detection. Maleimides selectively label thiols of cysteine residue via 1,4-addition pathway, without interacting with amines, to form thioether linkage. Maleimides apparently do not react with methionine, histidine or tyrosine, but they might react with primary amines under strong basic environment. BioActs offers Flamma® 552 maleimide for labeling of thiols on antibodies, peptides, proteins, ligands and amplification substrates optimized for cellular labeling and detection.
Citation & Reference
1. Xu, Peisheng. Zwitterionic chitosan derivatives for pH-sensitive stealth coating. Biomacromolecules 11.9 (2010): 2352-2358.
2. Ibrahim, Basma M. A strategy to deliver genes to cystic fibrosis lungs: a battle with environment. Journal of controlled release 155.2 (2011): 289-295.
3. Oh, Keun Sang. Accurate sequential detection of primary tumor and metastatic lymphatics using a temperature-induced phase transition nanoparticulate system. International journal of nanomedicine 9 (2014): 2955.
4. Yhee, Ji Young. Tumor-targeting transferrin nanoparticles for systemic polymerized siRNA delivery in tumor-bearing mice. Bioconjugate chemistry 24.11 (2013): 1850-1860.
5. Yoon, Hong Yeol. Glycol chitosan nanoparticles as specialized cancer therapeutic vehicles: Sequential delivery of doxorubicin and Bcl-2 siRNA. Scientific reports 4 (2014).
6. Ryu, Ju Hee. Early diagnosis of arthritis in mice with collagen?induced arthritis, using a fluorogenic matrix metalloproteinase 3–specific polymeric probe. Arthritis & Rheumatism 63.12 (2011): 3824-3832.
7. Hollis, Christin P. In vivo investigation of hybrid paclitaxel nanocrystals with dual fluorescent probes for cancer theranostics. Pharmaceutical research 31.6 (2014): 1450-1459.
8. Koo, Heebeom. The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection. Biomaterials 33.12 (2012): 3485-3493.
9. Zhu, Lei. Real-time monitoring of caspase cascade activation in living cells. Journal of controlled release 163.1 (2012): 55-62.
10. Yoon, Hong Yeol. Bioreducible hyaluronic acid conjugates as siRNA carrier for tumor targeting. Journal of Controlled Release 172.3 (2013): 653-661.
11. Yhee, Ji Young. Cancer-targeted MDR-1 siRNA delivery using self-cross-linked glycol chitosan nanoparticles to overcome drug resistance. Journal of Controlled Release 198 (2015): 1-9.
12. Park, Jin Woo. Wide-Ranged Fluorescent Molecular Weight Size Markers for Electrophoresis. Bulletin of the Korean Chemical Society 34.1 (2013): 29-30.
13. Huang, Xinglu. Multiplex Imaging of an Intracellular Proteolytic Cascade by using a Broad?Spectrum Nanoquencher. Angewandte Chemie International Edition 51.7 (2012): 1625-1630.
OPTION
Total
$0
Added cart
We put the items
in the shopping cart.
