Description

Lectin-FSD 488 is a fluorescence labeled carbohydrate binding protein or glycoprotein that FSD fluorophore is covalently attached to lectin. The maxima of Ex/Em values are at 495/521 nm. Lectins display high, specific affinity to sugar residues thereby enable to distinguish subtle alteration in glycosylation otherwise indistinguishable cells. FSD 488 is a bright green dye that developed by BioActs’ cutting-edge technology displaying excellent optical property comparing to spectrally similar dyes. Fluorescence-conjugated lectins are versatile carbohydrate detecting probes in microscopy, histochemistry and flow cytometry. BioActs offers Lectin-FSD 488 for the identification of various cellular carbohydrates. 

Specifications

Functionality: Fluorescent protein

Fluorophore: FSD Fluor™ 488

Excitation/Emission Max.(nm): 495/521

Molecular weight: ~≥ 71 KDa

Appearance: Yellow Liquid

Concentration: 1 mg/mL in proper buffer

Storage conditions: 4 ℃, protect from light

Citation & Reference

1. Park JM, High-speed clearing and high-resolution staining for analysis of various markers for neurons and vessels. Tissue Engineering and Regenerative Medicine. 2024 Jul 2;21(7):1037–48. 


2. Mali NM, Deep tissue clearing for three-dimensional imaging analysis of murine pancreas. Anatomy & Biological Anthropology. 2022;35(2):57. 

 

3. Kang G-Y,  3D imaging of the transparent mycobacterium tuberculosis-infected lung verifies the localization of innate immune cells with granuloma. Frontiers in Cellular and Infection Microbiology. 2020 May 15;10.

 

4. Xiao-Peng He. Fluorescent glycoprobes: a sweet addition for improved sensing. Chem. Commun 53 (2017): 82-90.


5. Xiuli Dan. Development and Applications of Lectins as Biological Tools in Biomedical Research. Med Res Rev 36.2 (2016): 221-47.


6. Gijs Hendrik KleinJan. Fluorescent Lectins for Local in Vivo Visualization of Peripheral Nerves. Molecules 19.7 (2014): 9876-92.


7. Bird-Lieberman EL. Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus. Nat Med 18.2 (2012): 315-21.a

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